Detalhe da pesquisa
1.
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.
Cell
; 183(7): 1848-1866.e26, 2020 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301708
2.
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Cell
; 167(4): 985-1000.e21, 2016 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27881304
3.
Chemical and Physiological Features of Mitochondrial Acylation.
Mol Cell
; 72(4): 610-624, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444998
4.
Development of a colorimetric α-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins.
J Biol Chem
; 296: 100397, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571527
5.
Nucleosome competition reveals processive acetylation by the SAGA HAT module.
Proc Natl Acad Sci U S A
; 112(40): E5461-70, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26401015
6.
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.
Mol Cell Proteomics
; 13(11): 2896-910, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25106422
7.
Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination.
PLoS Genet
; 9(10): e1003871, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24146631
8.
A conserved asparagine has a structural role in ubiquitin-conjugating enzymes.
Nat Chem Biol
; 9(3): 154-6, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292652
9.
Age-associated remodeling of T cell immunity and metabolism.
Cell Metab
; 35(1): 36-55, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36473467
10.
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers.
PLoS One
; 17(9): e0261803, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067168
11.
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function.
Science
; 377(6614): 1519-1529, 2022 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36173860
12.
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells.
Cancer Immunol Res
; 9(2): 184-199, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277233
13.
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway.
Nat Commun
; 11(1): 6164, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268780
14.
Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming.
Cell Syst
; 8(5): 412-426.e7, 2019 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31078528
15.
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
Science
; 363(6432): 1217-1222, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30872525
16.
Mutations that Allow SIR2 Orthologs to Function in a NAD+-Depleted Environment.
Cell Rep
; 18(10): 2310-2319, 2017 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273448
17.
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Science
; 358(6365): 941-946, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29025995
18.
Structural basis for acyl-group discrimination by human Gcn5L2.
Acta Crystallogr D Struct Biol
; 72(Pt 7): 841-8, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27377381
19.
Structural basis for histone H2B deubiquitination by the SAGA DUB module.
Science
; 351(6274): 725-8, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912860
20.
Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2.
Protein Sci
; 23(12): 1686-97, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25200501